Neuroscience/Neuropathology/Trauma and epilepsy

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See also: Neuroscience/Brain injury

Objectives

  • Describe the gross and microscopic (when appropriate) appearance, mechanism of production, clinical presentation, and prognosis of
    • Skull fractures
    • Epidural hematomata
    • Subdural hematoma
    • Contusions (coup and counter-coup)
    • Diffuse axonal injury
    • Ponto-medullary rent
    • Spinal cord injuries
  • List the lesions most likely to cause post-traumatic deterioration (Edema, ischemia, hematomata, infection, hydrocephalus)
  • Indicate the common pathological substrates of:
    • Primary generalized epilepsy
    • Temporal lobe epilepsy
    • Other seizures of focal onset
  • Indicate the mechanism of production of mesial temporal sclerosis.

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Notes

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